陈春霞

发布时间:2019-11-13文章来源: 浏览次数:

陈春霞,教授,博士研究生导师,化学化工与资源利用学院院长,黑龙江省化学学会副理事长,林学会高级会员,中国化学会会员。20077月毕业于中科院成都有机化学研究所,获应用化学博士学位,同年作为引进人才入职东林工作至今。2010-2013年在东北林业大学林业工程博士后流动站从事科学研究工作。

通讯地址:哈尔滨市和兴路26号化学化工与资源利用学院,邮编150040

E-mail: ccx1759@163.com

所在学科

化学学科(博导/硕导),材料与化工(专硕)

研究领域/科研成果

主要从事植物源天然产物的结构修饰与生物活性及农药创制研究。在《Organic Letters》、《Journal of Organic Chemistry》、《Journal of Colloid and Interface Science》、《Advanced Healthcare Materials》、《Journal of Environmental Chemical Engineering》、《Coordination Chemistry Reviews》等期刊上发表SCI收录论文70余篇(JCR Q1区论文30篇),影响因子总和超过300H因子21,被引用1400余次。出版专著2部,获得授权专利3项;主持国家自然科学青年和面上基金、黑龙江省自然科学重点和面上基金、教育部博士点新教师类基金、国家和黑龙江省博士后科学基金、中央高校杰出青年人才基金项目等10余项,经费近400万元。

代表性学术论文

[1] Baichuan Mo, Zhanyu Li, Jinsong Peng*, Chunxia Chen*. Novel lignin-supported copper complex as a highly efficient and recyclable nanocatalyst for Ullmann reaction. International Journal of Biological Macromolecules, 2023, 239, 124263.

[2] Baichuan Mo, Chunxia Chen*, Jinsong Peng*. CuI-Catalyzed Synthesis of Multisubstituted Pyrido[1,2-a]pyrimidin-4-ones Through Tandem Ullmann-type C-N Cross-Coupling and Intramolecular Amidation Reaction. RSC Advances, 2023,13: 24264-24271.

[3]  Baichuan Mo, Chunxia Chen*, and Jinsong Peng*. Research Progress in Application of Lignin and Its Derivatives Supported Metal Catalysts in Organic Synthesis [J]. Chinese Journal of Organic Chemistry, 2023, 43(4): 1215-1240.

[4]  Peiji Yin, Yixuan Chen, Yu Wang, Yujing Chi, Bokai Li, Mingwei Xu, Haiyan Song *, Chunxia Chen*, Hydroxyl modified nano calcium phosphate, a novel adsorbent fordenitrogenation of fuel: Synthesis, characterization and adsorptiveperformance for quinoline, Journal of Environmental Chemical Engineering, 2023,11,110374.

[5]  Jiale Liu, Mengyao Huang, Xingyu Zhang, Zhongyu Hua, Zeran Feng,Yi Dong, Tiedong Sun*, Xiao SunChunxia Chen*,Polyoxometalate nanomaterials for enhanced reactive oxygen species theranostics, Coordination Chemistry Reviews, 2022,472,214785.

[6] Zhaocong Zhang, Chengwen Ding, Tiedong Sun*, Lei Wang*, Chunxia Chen*, Tumor Therapy Strategies Based on Microenvironment-Specific Responsive Nanomaterials, Advanced Healthcare Materials, 2023, 2302028.

[7]  Jingqi Li, Xinda Cai, Peng Jiang, Huayuan Wang, Shiwei Zhang, Tiedong Sun,* ChunxiaChen,*and Kelong Fan*, Co-based Nanozymatic Profiling: Advances Spanning Chemistry, Biomedical, and Environmental Sciences, Advanced Materials, 2023, e2307337 .

[8] Dun Zhou, Aihong Fan, Xiang Li, Chunxia Chen*, Peng Sun, Jinsong Peng*. Copper-Catalyzed Decarboxylative Cross-Coupling of Carboxylic Acids and Arylcarbamoyl Chlorides, Chin. J. Org. Chem. 2021, 41: 1146-1152.

[9] 陈鑫, 陈春霞*, 彭进松*. 纤维素及其衍生物负载铜催化有机反应的研究进展,有机化学, 2021, 41 1319-1336.

[10] Xin Chen,  Peng Sun, Baichuan Mo, Chunxia Chen*, Jinsong Peng*. Palladium-Catalyzed Synthesis of Fluorescent Benzo[4,5]imidazo[1,2-a]pyridines through Annulation Reaction of Benzimidazoles and Alkynyl Bromides with Internal Alkynes, J. Org. Chem., 2021, 86(1) : 352-366.

[11] Xiang Li, Peng Sun, Kaijun Xie, Dun Zhou, Jinsong Peng*, Aihong Fan, Jing Zhang, Chunxia Chen*. Transition-Metal-Free One-Pot Synthesis of Naphthoquinonefuran Derivatives Through Sequential Nucleophilic Substitution-Nucleophilic Addition Reaction, J. Org. Chem., 2020, 85(14): 9313-9320.

[12] Peng Sun, Jiaojiao Yang, Zirui Song, Yichao Cai , Yajie Liu, Chunxia Chen*, Xin Chen, Jinsong Peng*. Copper-Mediated One-Pot Synthesis of Indoles through Sequential Hydroamination and Cross-Dehydrogenative Coupling Reaction, Synthesis, 2020, 52: 72-84.

[13] Peng Sun, Jiaojiao Yang, Chunxia Chen*, Kaijun Xie, Jinsong Peng. Synthesis of a Cellulosic Pd(salen)‑Type Catalytic Complex as a Green and Recyclable Catalyst for Cross-Coupling Reactions, Catalysis Letters, 2020, 150: 2900–2910.

[14] Peng Sun, Jiaojiao Yang, Jinsong Peng*, BaiChuan Mo, Xin Chen, Xiang Li, Chunxia Chen*. Palladium(II)-Catalyzed Oxidative Annulation of 2-Hydroxynaphthalene-1,4-diones and Internal Alkynes via C-H Functionalization, J. Org. Chem., 2020, 85(10): 6761-6769.

[15] Aihong Fan, Jinsong Peng*, Dun Zhou, Xiang Li, Chunxia Chen*. Palladium-catalyzed decarbonylative C-N coupling to convert arylcarbamoyl chlorides to urea derivatives, Synthetic Communication, 2020, 50: 3113-3124.

[16] Xin Chen,  Yunyun Bian, Baichuan Mo, Peng Sun, Chunxia Chen*, Jinsong Peng*. Copper(II)-catalyzed synthesis of multisubstituted indoles through sequential Chan-Lam and cross-dehydrogenative coupling reactions, RSC Advances, 2020, 10: 24830-24839.

[17] 李雪, 宋子锐, 陈鑫, 蔡轶超, 刘雅婕, 陈春霞*, 彭进松*. 钯催化双芳基化反应合成咔唑醌衍生物的研究, 有机化学, 2020, 40: 950-958.

[18] Ruonan Liu, Yahui Wang, Shuxian Sun, Chunxia Chen, Xiaoliang Wu*. CoNi layered double hydroxide anchored on N-doped carbon coated carbon nanotubes network with 3D core-shell structure for all-solid-state supercapacitors, Journal of Electroanalytical Chemistry, 2020, 878: 114571-114576.

[19] Xue Li, Yunyun Bian, Xin Chen, Hang Zhang, Wei Wang, Sida Ren, Xuechen Yang, Chang Lu, Chunxia Chen*, Jinsong Peng*. Tunable synthesis of quinolinone-fused isoquinolines through sequential one-pot nucleophilic addition and palladium-catalyzed intramolecular C–H alkenylation, Org. Biomol. Chem., 2019, 17: 321-332.

[20] Xue Li,  Xin Chen,  Hui Wang,  Chunxia Chen*,  Peng Sun, Baichuan Mo, Jinsong Peng*. Palladium-catalyzed tandem one-pot synthesis of pi-expanded imidazoles through a sequential Heck and oxidative amination reaction, Org. Biomol. Chem., 2019, 17: 4014-4023.

[21] Jiang-An You, Haiyan Song*, Jin Zhang, Chunxia Chen,  Fuqin Han. Adsorptive removal of nitrogen-containing compounds from fuel over hierarchical porous aluminosilicates synthesized by kinetic regulation method, Fuel, 2019, 241: 997-1007.

[22] Yue Li, Jinsong Peng, Xin Chen, Baichuan Mo, Xue Li, Peng Sun, Chunxia Chen*. Copper-Catalyzed Synthesis of Multisubstituted Indoles through Tandem Ullmann-Type C-N Formation and Cross-dehydrogenative Coupling Reactions, J. Org. Chem., 2018, 83: 5288−5294.

[23] Jie Huang, Xibiao Zhang, Haiyan Song*, Chunxia Chen, Fuqin Han,  Congcong Wen. Protonated graphitic carbon nitride coated metal-organic frameworks with enhanced visible-light photocatalytic activity for contaminants degradation, Applied Surface Science, 2018, 441: 85-98.

[24]  Deqiang Wang, Peng Sun, Peiyun Jia, Jinsong Peng*, Yixia Yue, and Chunxia Chen*.Transition-Metal-Free One-Pot Tandem Synthesis of 4-Quinolone and 4H-Thiochromen-4-one Derivatives Through Sequential Nucleophilic Addition–Elimination–SNAr Reaction, Synthesis, 2017, 49: 4309-4320.

[25] Yixia Yue, Jinsong Peng*, Deqiang Wang,Yunyun Bian,Peng Sun, and Chunxia Chen*. Synthesis of 4H-Chromen-4-one Derivatives by Intramolecular Palladium-Catalyzed Acylation of Alkenyl Bromides with Aldehydes, J. Org. Chem., 2017, 82(10): 5481-5486.

[26] Yanhan Yu, Yixia Yue, Deqiang Wang, Xue Li, Chunxia Chen, and Jinsong Peng. Modular synthesis of quinazolinone-fused phenanthridinones by a palladium-catalyzed cascade C−H/N−H arylation process, Synthesis, 2016, 48: 3941-3950.

[27] Gongyuan Zhao, Chunxia Chen*, Yixia Yue, Yanhan Yu, Jinsong Peng*.  Palladium(II) -Catalyzed Sequential CH Arylation Aerobic Oxidative CH Amination: One-Pot Synthesis of Benzimidazole-Fused Phenanthridines from 2-Arylbenzimidazoles and Aryl Halides, J. Org. Chem., 2015, 80(5): 2827-2834.

[28] 段胜聪, 孟自珍, 解晶, 陈春霞*. 基于油菜花粉模板制备ZnAlCe三元复合氧化物多孔材料及其催化性能研究, 无机材料学报, 2015, 30(4): 420-426.

[29] 高翯, 王翰旸, 黄章杰, 姚丽萍, 彭进松, 陈春霞*. 铜催化2-苄基苯并咪唑衍生物氧气氧化反应的研究. 有机化学, 2015, 35: 1707-1714.

[30] Yinghua Wang, Hanyu Liang, Chunxia Chen*, Deqiang Wang, Jinsong Peng*. One-pot synthesis of 4-quinolone derivatives through sequential Michael addition-elimination/ Pd-catalyzed Buchwald-Hartwig amination reaction, Synthesis, 2015, 47: 1851-1860.

[31] Hanyang Wang, Chunxia Chen, Zhangjie Huang, Liping Yao, Bin Li, Jinsong Peng*. Palladium-Catalyzed Double C–H Arylation Reaction: Tandem Synthesis of Benzo[a]imidazo[5,1,2-cd]indolizines from Imidazo[1,2-a]pyridines and o-Dihaloarenes, Synthesis, 2015, 47: 2457-2466.

[32]  段胜聪, 李雪, 李悦, 陈春霞*. 淀粉模板法制备复合金属氧化物及其催化α-蒎烯氧化性能的研究. 分子催化, 2015, 29(4): 339-347.

[33] Chunxia Chen*, Guoning Shang, Jingjie Zhou, Yanhan Yu, Bin Li, Jinsong Peng*. Modular Synthesis of Benzimidazole-Fused Phenanthridines from 2-Arylbenzimidazoles and o-Dibromoarenes by a Palladium-Catalyzed Cascade Process, Org. Lett.,2014, 16: 1872-1875.

[34] Jinsong Peng, Yan Zhao, Jingjie Zhou, Yuehang Ding, Chunxia Chen*, Synthesis of Dihydropyrrole Derivatives by a Palladium-Catalyzed Heck and Suzuki Cross-Coupling Cascade Reaction, Synthesis, 2014, 46: 2051-2056.

[35]于敬阳, 彭进松, 岳亦霞, 赵宇卓, 陈春霞*. 无过渡金属催化条件下咪唑衍生物与炔基溴的炔基化反应研究, 有机化学, 2014, 34: 1352-1357.

[36] Jinsong Peng, Guoning Shang, Chunxia Chen, Zhongshuo Miao, Bin Li*. Nucleophilic Addition of Benzimidazoles to Alkynyl Bromides/Palladium- Catalyzed Intramolecular C-H Vinylation: Synthesis of Benzo[4,5]imidazo [2,1-a]isoquinolinesJ. Org. Chem., 2013, 78: 1242-1248.

[37]  Chunxia Chen, Yanchun Hou, Bin Li*, Wuzhong Yi. Sodium Dodecyl Benzene Sulfonate Modified Layered Double Hydroxides as a Photocatalyst Under Simulated Solar Radiation for Removal of Malachite Green, Asian J. Chem., 2013, 25(6): 3167-3171.

[38] Han Zhang, Guangliang Liu, Haiyan Song *, Chunxia Chen, et al. Direct Synthesis of H2O2 over Ti-Containing Molecular Sieves Supported Gold Catalysts: A Comparative Study for In-situ-H2O2-ODS of Fuel, Bulletin of the Korean Chemical Society, 2013, 34(10): 3065-3072.

[39]  Chunxia Chen, Chen Chen, Bin Li*, Jingwei Tao, Jinsong Peng, Aqueous Synthesis of 1-H-2-Substituted Benzimidazoles via Transition-Metal-Free Intramolecular Amination of Aryl Iodides, Molecules, 2012, 17: 12506-12520.

[40] Chunxia Chen, Rong Xu, Bin Li*. Controlled/Living ring-opening polymerization of ε-caprolactone catalyzed by phosphoric acid, Sci. China Chem., 2012, 55 (7): 1257-1262.

[41] 许茸, 陈春霞*. 有机小分子催化ε-己内酯开环聚合反应研究进展, 化学进展, 2012, 24(8): 1519-1525.

[42] Wang Lili, Li Bin*, Zhao Xiaohong, Chen Chunxia, Cao Jingjing. Effect of Rare Earth Ions on the Properties of Composites Composed of Ethylene Vinyl Acetate Copolymer and Layered Double Hydroxides, PLoS One, 2012, 7(6) e37781: 1-8.

[43] Wang Lili, Li Bin*, Zhang Xiucheng, Chen Chunxia, Zhang Feng. Effect of intercalated anions on the performance of Ni–Al LDH nanofiller of ethylene vinyl acetate composites, Applied Clay Science, 2012, 56: 110 -119.

[44] Jinsong Peng, Tonghui Chen, Chunxia Chen, Bin Li*. Palladium-Catalyzed Intramolecular C-H Activation/C-C Bond FormationA Straightforward Synthesis of Phenanthridines, J. Org. Chem., 2011, 76: 9507-9513.

[45]  Jinsong Peng, Min Ye, Cuijuan Zong, Fangyun Hu, Lingtong Feng, Xiaoyan Wang, Yufeng Wang, Chunxia Chen*. Copper-Catalyzed Intramolecular C−N Bond Formation: A Straightforward Synthesis of Benzimidazole Derivatives in Water, J. Org. Chem., 2011, 76: 716-719.

[46] Jinsong Peng, Cuijuan Zong, Min Ye, Tonghui Chen, Dewei Gao, Yufeng Wang, Chunxia Chen*. Direct Transition-Metal-Free Intramolecular C-O Bond Formation: Synthesis of Benzoxazole Derivatives, Org. Biomol. Chem., 2011, 9: 1225-1230.

[47] Wang Lili, Li Bin*, Yang Mingfei, Chen Chunxia, Liu Yongsheng. Effect of Ni cations and microwave hydrothermal treatment on the related properties of layered double hydroxide–ethylene vinyl acetate copolymer composites, Journal of Colloid and Interface Science, 2011, 356: 519-525.

[48] Wang Yufeng, Song Zhanbo, Chen Chunxia, Peng Jinsong*. Pictet-Spengler condensation reactions catalyzed by a recyclable H+-montmorillonite as a heterogeneous Brønsted acid, Sci. China Chem., 2010, 53: 562-568.

[49] Wang Lili, Li Bin*, Chen Chunxia, Jia Lina. Structural characterization and related properties of the stearate anions intercalated Ni–Al hydrotalcite-like compound prepared by the microwave crystallization, Journal of Alloys and Compounds, 2010, 508: 426-432.

[50]  Chunxia Chen*, Jinsong Peng, Bin Li, Lili Wang. The catalytic Baeyer-Villiger oxidation of cyclohexanone to ε-caprolactone over stibium-containing hydrotalcite, Catal. Lett., 2009, 131: 618-623.

[51]   Chunxia Chen*, Jinsong Peng, Bin Li, Zhongqin Hu, Hua Zhang, Fali Qiu. The Catalytic Activity of CuNi-Containing Hydrotalcites in the Transesterification of Dimethyl Oxalate with Phenol, J. Porous Mat., 2009, 16(2): 233-238.

[52] Chunxia Chen*, Chenghua Xu, Liangrong Feng, Jishuan Suo, Fali Qiu*. Deactivation and reactivation of copper-containing pentatomic hydrotalcite in catalytic hydroxylation of phenol, J. Mol. Catal. A Chem., 2006, 252: 171-175.

[53]   Chunxia Chen, Chenghua Xu, Liangrong Feng, Jishuan Suo, Fali Qiu*. Phenol Hydroxylation Catalyzed by the Rare Earth-adulterated Copper-containing Hydrotalcites, Chem. Lett., 2005, 342: 206-207.

[54] Chunxia Chen*, Chenghua Xu, Liangrong Feng, Jishuan Suo, Fali Qiu*. Kinetics and reaction mechanism of phenol hydroxylation catalyzed by La-CuFeAlCO3, Sci. China Chem., 2005, 48(6): 530-537.

[55]   Chunxia Chen, Chenghua Xu*, Liangrong Feng, Zijian Li, Jishuan Suo, Fali Qiu*, Yingchun Yang. Effect of rare earth doping on the catalytic activity of copper-containing hydrotalcites in phenol hydroxylation, Adv. Synth. Catal., 2005, 347: 1848-1854.

主要科研项目

1.吲哚生物碱防治松材线虫病农药的创制、构效关系与作用机制,国家自然科学面上基金,50万,2024.01-2027.12,主持人。

2. 咔唑醌生物碱合成与抗肿瘤构效关系及作用机制研究,黑龙江省自然科学基金重点项目,50万,2021.07-2024.06,主持人。

3.  吴茱萸喹诺酮生物碱及衍生物抗肿瘤作用机制与构效关系的研究,国家自然科学青年基金项目,24万,2015.01-2017.12,主持人。

4. 甲磺酸溴隐亭中间体,成都倍特药业股份有限公司技术开发委托项目,56万,2020.09 - 2023.08,主持人。

5.  六氢吡咯并吲哚生物碱抗肿瘤生物活性研究,黑龙江省自然科学面上项目,6万,2017.10-2020.10,主持人。

6.  HPI生物碱及衍生物的合成及应用研究,中央高校杰出青年科研人才基金项目,35万,2017.03-2020.02,主持人。

7.  基于生物模板多金属复合氧化物孔材料的制备及其催化性能的研究,黑龙江省博士后科研启动金,10万,2015.01-2016.12,主持人。

8.   蒎烯环氧化催化材料的研究,教育部博士点新教师类基金,4万,2013.01-2015.12,主持人。

9.   铜催化碳-杂交叉偶联反应的研究,中国博士后科学基金,3万,2011.01-2012.12,主持人。

10.  纳米层状双氢氧化物的自组装及在污水处理中的应用研究,黑龙江省博士后基金,4万,2011.01-2012.12,主持人。

11.  纳米稀土层状双氢氧化物的可控制备及阻燃性能的研究,哈尔滨市科技创新人才研究专项资金项目,4.05万,2008.10-2010.10,主持人。

12.  纳米水滑石的合成与阻燃性能研究,黑龙江省普通高等学校青年学术骨干支持计划项目,2万,2010.01-2013.12,主持人。

13. 纤维素/LDHs纳米复合材料的制备及光催化降解废水中染料的研究,中央高校基本科研业务费专项资金项目,9万,2011.06-2013.11,主持人。

14.  纳米材料的制备及其应用研究,东北林业大学青年拔尖人才支持计划项目,4万,2012.01-2013.12,主持人。

15.  纳米LDHs催化Baeyer-Villiger反应的研究,东北林业大学引进人才启动基金项目,10万,2008.01-2010.12,主持人。

专著与教材

1. 彭进松,陈春霞. 过渡金属催化碳-碳单键活化与重组,科学出版社,30万字,2017

2. 陈春霞. 新型无机功能材料层状双氢氧化物,黑龙江省科学技术出版社,15万字,2012

3. 贾佩云,陈春霞,周志强,曹晶晶. 无机及分析化学实验(高等学校十二五规划教材),化学工业出版社,39.8万字,2013

4.  胡忠勤,贾佩云,陈春霞,曹晶晶. 无机与分析化学学习指导,东北林业大学出版社,79.6万字,2012

5. 韩福芹主编,王丽丽和曹晶晶副主编, 陈春霞(主 审),无机化学实验(教材),化学工业出版社(普通高等教育十三五规划教材),2019

专利

1.  陈春霞,赵汉青,彭进松,许茸. 柱撑水滑石的制备方法,国家发明专利,专利号ZL201010270630.220121月授权。

2.  陈春霞,侯艳春,李斌. 一种含钛纤维素/LDHs纳米复合材料及其制备方法和应用,国家发明专利,专利号ZL201210036617.X20139月授权。

3. 陈春霞,孟自珍,段胜聪,彭进松. 一种双金属复合氧化物多孔材料及其制备方法和应用,国家发明专利,ZL20141040429620164月授权。

教学改革

1.课程思政视域下新农科基础化学课程教学改革与实践,黑龙江省高等教育教学改革研究项目,2022-2024,主持人。

2.高等农林院校大类招生培养模式下教学改革与实践,黑龙江省高等教育教学改革研究项目,2018-2020,主持人。

3.新农科基础化学课程体系与新形态教材建设,教育部新农科研究与改革实践项目,2020-2023,参加人。

4.化学学科和专业支持四新建设思路和路径研究,中国高等教育学会理科教育研究专题课题,2021-2024,参加人。

5. 无机化学课程课堂教学与考试方法改革的研究,黑龙江省教改项目,2014.06-2016.09,主持人。

6. 东北林业大学无机化学1在线课程建设项目,2020-2022,主持人。

7. 东北林业大学无机化学A重点课程建设项目,2012-2014,主持人。

教学/科研获奖

1. 知行合一、夯基立新,服务新农科战略的基础化学课程教学改革与实践,黑龙江省高等教育教学成果二等奖,第一获奖人,2022

2. 绿色催化氧化新方法在杂环合成与降解反应中的应用基础研究,校成栋科技自然科学二等奖,第一获奖人,2022

3. 服务新农科战略的基础化学课程教学改革与实践,东北林业大学教学成果奖,第一获奖人,2021

4. 无机化学类课程课堂教学与考试方法改革和实践,东北林业大学教学成果奖,第一获奖人,2017

5. 东北林业大学2023年十佳研究生导师奖,2023

6. 东北林业大学2018-2019学年本科教学改革优秀奖,2019

7. 东北林业大学2019-2020学年本科生导师优秀奖,2020



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