杨磊

发布时间:2019-11-13文章来源: 浏览次数:


杨磊,教授,男,196410月出生,博士,博士生导师。1994年就职于东北林业大学;1998年在东北林业大学木材科学与技术专业获工学博士学位,师从李坚院士;博士期间赴日本国立岛根大学生物材料工学科合作研究;2005-2007年在浙江海正集团博士后工作站从事植物活性成分功能化的博士后研究。获得国家技术发明二等奖1项,教育部技术发明一等奖1项,二等奖1项,教育部自然科学二等奖1项,黑龙江省自然科学二等奖1项,四川省科技进步二等奖1项。申请国家发明专利42项,获得授权10项,撰写学术专著5部,2011年任现职至今,已发表SCI收录学术论文126篇,其中第一作者和通讯作者论文86篇。


招生专业:学博:化学一级学科(林源化学二级学科);

学硕:药学一级学科(药物化学二级学科);

专硕:药学(生药学方向)。

联系邮箱:yanglei_nefu@126.com


教学情况:

主讲研究生课程包括天然药物化学(硕士)、药物化学原理(硕士)、药物化学文献阅读及方法创新(硕士)、植物资源学(博士)、先进林源化学品学(博士)、林源化学前沿(博士)


科学研究方向:

1 环境友好溶剂分离分析植物目标活性成分;

2 微波和超声等新技术在植物活性成分分离中的应用;

3 新型环境友好催化剂实现目标植物成分转化增量;

4 我国主要林源树种及林下资源生态化学利用;

5 木本油料的清洁化制备及稳定性研究;

6 制备生物活性组分微纳米粒子实现减毒增效利用;

7 植物活性成分分离剩余物的资源化再利用。


近年研究课题:

1. 林业公益性行业科研专项:林木生物质液体燃料的制备及其综合利用技术(201304601)合同经费840万元2013.1-2016.12项目主持人;

2. 林业公益性行业科研专项:油樟和山桐子活性组分制备及效应(201404602)合同经费69万元2014.1-2016.12项目主持人;

3. 林业公益性行业科研专项:奎尼酸提取分离和纯化工艺研究(2014046160102)合同经费16万元2014.1-2016.12项目主持人;

4. 林业公益性行业科研专项:牡丹种皮多酚的分离纯化工艺研究(20140470102-04)合同经费:40万元2014.1-2018.12项目主持人;

5. 黑龙江省科学基金:杜香精油等成分多级制备及对黄芪根腐致病菌抑制机制的研究(C2018005)合同经费:6万元2018.1-2021.12项目主持人;

6. 林业公益性行业科研专项:水溶性杜仲全价提取物分离创新技术研制(201504701-2-2)合同经费:40万元2015.1-2019.12项目主持人;

7. 国家自然科学基金(面上):木本植物原花色素分级、纳米化制备表征及抗氧化抗辐射活性相关性(31670580)合同经费:65万元2017.1-2020.12项目主持人;

8. 国家自然科学基金(面上):植物精油的分离新策略:离子液体-酶复合体系的构建32271794)直接经费:54万元2023.1-2026.12项目主持人.


科研获奖:

国家技术发明二等奖,2006年度,茄尼醇高效提取纯化生产新工艺,第二获奖人

教育部高等学校科学技术奖技术发明一等奖,2005年度,第二获奖人

教育部高等学校科学技术奖技术发明二等奖,2007年度,第二获奖人

黑龙江省自然科学二等奖,2014年度,第四获奖人

教育部高等学校科学技术奖二等奖,2019年度,第二获奖人

四川省科技进步二等奖,2019年度,第四获奖人

梁希林业科学技术奖自然科学二等奖,2019年度,第二获奖人

梁希林业科学技术奖自然科学二等奖,2021年度,第三获奖人


近年发表的主要SCI学术论文:

1. Yao Xiao, Zaizhi Liu, Huiyan Gu, Lei Yang*, Tingting Liu*, Hao Tian. (2024). Preparation and characterization of a modified Canna starch as a wall material for the encapsulation of methyleugenol improves its antifungal activity against Fusarium trichothecioides. Food Chemistry, 433,137324.

2. Xing Yin, Ru Zhao, Aoqi Zhang, Tingting Liu, Yefei Zhou, Changwen Fan, Ailing Ben, Lei Yang*, Xiaoyu Sui*. (2023). Efficient ultrasound-assisted extraction of platycodin D and lobetyolin from Platycodon grandiflorus with polyethylene glycol (PEG) solution. Industrial Crops and Products, 191A, 115951.

3. Yao Xiao, Ru Zhao, Zaizhi Liu, Lin Zhang, Huiyan Gu, Fengjian Yang*, Lei Yang*, Tingting Liu*. (2023). An efficient method to obtain essential oil from Asarum heterotropoides via homogenate-microwave-assisted hydrodistillation and evaluation of Fusarium species inhibition activity in vitro compared to its main components. Industrial Crops and Products, 194, 116366.

4. Zehao Wang, Ru Zhao, Hongfei Gao, Yang Yang, Xinyu Yang, Huiyan Gu, Lei Yang*, Xiaonan Zhang*, Tingting Liu*. (2023). Solvent-free microwave extraction of essential oil and hydrosol from fresh leaves of Cinnamomum burmannii (Nees et T. Nees) Blume after screw extrusion treatment and evaluation of pancreatic lipase inhibitory activities in vitro compared to its main components. Industrial Crops and Products, 202, 116983.

5. Hongfei Gao, Ru Zhao, Changwen Fan, Yang Yang, Zehao Wang, Huiyan Gu*, Lei Yang*, Hao Tian, Qiang Zhang, Xiaonan Zhang*. (2023). An efficient approach to obtain essential oil, oleanoic acid, 3-O-acetyloleanolic acid and betulinic acid from fresh leaves of Melaleuca bracteata F. Muell. 'Revolution Gold' using microwave and gravity-assisted solvent-free distillation followed by extraction. Industrial Crops and Products, 203, 117178.

6. Xinyu Yang, Ru Zhao, Mengxia Wei, Huiyan Gu, Jialei Li, Lei Yang*, Tingting Liu*. (2022). An improved approach of salting-out solvent-free microwave mediated rotary distillation for essential oil preparation from fresh leaves of magnolia (Oyama sieboldii). Food Chemistry: X, 16, 100524.

7. Aoqi Zhang, Ru Zhao, Yunxia Wang, Tingting Liu, Hao Tian, Xing Yin, Lei Yang*, Xiaoyu Sui*. (2022). Natural surfactant used as an additive in the homogenate-ultrasound-synergistic extraction of regaloside A and polysaccharides from Lilium lancifolium bulbs using Doehlert matrix design. Industrial Crops and Products, 188 A, 115689.

9. Xiaojin Peng, Ru Zhao, Xinyu Yang, Chunte Feng, Huiyan Gu, Lei Yang*. (2022). Separation of essential oil from fresh leaves of Phellodendron amurense Rupr. by solvent-free microwave-assisted distillation with the addition of lithium salts. Journal of Cleaner Production, 372, 133772.

10. Xinyu Yang, Ru Zhao, Han Wang, Ailing Ben, Hong Lin, Xiaonan Zhang, Chunying Li*, Lei Yang*. (2022). Resin adsorption as a means for the enrichment and separation of three terpenoid indole alkaloids: Vindoline, catharanthine and vinblastine from Catharanthus roseus extracts in ionic liquid solution. Industrial Crops and Products, 197, 115351.

11. Ru Zhao, Ailing Ben, Mengxia Wei, Ming Ruan, Huiyan Gu*, Lei Yang*. (2022). Essential oil obtained from Thlaspi arvense L. leaves and seeds using microwave-assisted hydrodistillation and extraction in situ by vegetable oil and its antifungal activity against Penicillium expansum. LWT, 165, 113718.

12. Guoqiang Cui, Xinyu Yang, Zaizhi Liu, Mengxia Wei, Tingting Liu, Huiyan Gu*, Lei Yang*. (2022). Potential use of limonene as an alternative solvent for extraction of gutta-percha from Eucommia ulmoides. ACS Sustainable Chemistry & Engineering. 10, 1105711068.

13. Xinyu Yang, Tingting Liu, Shuwen Qi, Huiyan Gu*, Jialei Li, Lei Yang*. (2022). Tea saponin additive to extract eleutheroside B and E from Eleutherococcus senticosus by ultrasonic mediation and its application in a semi-pilot scale. Ultrasonics Sonochemistry, 86, 106039.

14. Xinyu Yang, Tingting Liu, Mengxia Wei, Ru Zhao, Huiyan Gu*, Jialei Li, Fengli Chen, Lei Yang*. (2022). A modified microwave hydrodistillation and simultaneous extraction in a rotating state to obtain essential oil, rosmarinic acid, and polysaccharides with sucrose stearate as an additive from Perilla frutescens. Industrial Crops and Products, 181, 114807.

15. Ru Zhao, Xinyu Yang, Aoqi Zhang, Tieyang Zhou, Yunwei Zhou*, Lei Yang*. (2022). An efficient approach for simultaneously obtaining oil and epigoitrin from Orychophragmus violaceus seeds by microwave-mediated immiscible binary solvent extraction. Food Chemistry, 372, 131258.

16. Ru Zhao, Xinyu Yang, Muzhi Li, Xiaojin Peng, Mengxia Wei, Xiucheng Zhang*, Lei Yang*, Jialei Li. (2021). Biodiesel preparation from Thlaspi arvense L. seed oil utilizing a novel ionic liquid core-shell magnetic catalyst. Industrial Crops and Products, 162, 113316.

17. Xiaojin Peng, Xinyu Yang, Huiyan Gu*, Lei Yang*, Hongfei Gao. (2021). Essential oil extraction from fresh needles of Pinus pumila (Pall.) Regel using a solvent-free microwave-assisted methodology and an evaluation of acetylcholinesterase inhibition activity in vitro compared to that of its main components. Industrial Crops and Products, 167, 113549.

18. Xiaojin Peng, Xiaoyu Sui, Jialei Li, Tingting Liu*, Lei Yang*. (2021). Development of a novel functionality for a highly efficient imidazole-based ionic liquid non-aqueous solvent system for the complete extraction of target alkaloids from Phellodendron amurense Rupr. under ultrasound-assisted conditions. Industrial Crops and Products, 168, 113596.

19. Xiaojin Peng, Chunte Feng, Xun Wang, Huiyan Gu, Jialei Li, Xiaonan Zhang, Xiucheng Zhang*, Lei Yang*. (2021). Chemical composition and antioxidant activity of essential oils from barks of Pinus pumila using microwave-assisted hydrodistillation after screw extrusion treatment. Industrial Crops and Products, 166, 113489.

20. Ru Zhao, Mengxia Wei, Guangyu Shi, Xun Wang, Hongfei Gao, Lin Zhang*, Lei Yang*, Huiyan Gu. (2021). One-pot process for simultaneously obtaining oil and sinigrin from field pennycress (Thlaspi arvense) seeds using microwave-assisted biphasic extraction. Industrial Crops and Products, 166, 113483.

21. Yao Xiao, Zaizhi Liu, Huiyan Gu, Fengjian Yang, Lin Zhang*, Lei Yang*. (2021). Improved method to obtain essential oil, asarinin and sesamin from Asarum heterotropoides var. mandshuricum using microwave-assisted steam distillation followed by solvent extraction and antifungal activity of essential oil against Fusarium spp. Industrial Crops and Products, 162, 113295.

22. Fengli Chen*, Yao Xiao, Bingwen Zhang, Ruigang Chang, Duqiang Luo, Lei Yang*, Yongfan Yang, Dongmei Liu. (2020). Magnetically stabilized bed packed with synthesized magnetic silicone loaded with ionic liquid particles for efficient enrichment of flavonoids from tree peony petals. Journal of Chromatography A, 1613, 460671.

23. Qiang Zhang, Ruiyun Huo, Yibo Ma, Shuangmei Yan, Lei Yang*, Fengli Chen*. (2020). A novel microwave-assisted steam distillation approach for separation of essential oil from tree peony (Paeonia suffruticosa Andrews) petals: Optimization, kinetic, chemical composition and antioxidant activity. Industrial Crops and Products, 154, 112669.

24. Fengli Chen*, Xinyu Yang, Yibo Ma, Xiaoxia Wang, Duqiang Luo, Lei Yang*, Yongfan Yang. (2020). Synthesis and application of novel silver magnetic amino silicone adhesive particles for preparation of high purity α-linolenic acid from tree peony seed oil under applied magnetic field. Journal of Chromatography A, 1610, 460540.

25. Kexin Hou, Meili Bao, Lu Wang, Hua Zhang, Lei Yang, Haitian Zhao, Zhenyu Wang*.(2019). Aqueous enzymatic pretreatment ionic liquid–lithium salt based microwave–assisted extraction of essential oil and procyanidins from pinecones of Pinus koraiensis. Journal of Cleaner Production, 236, 117581.

26. Yusong Jin, Yunhui Zhang, Dongmei Liu, Dewen Liu, Chunying Zhang, Huijuan Qi, Huiyan Gu, Lei Yang*, Zhiqiang Zhou*. (2019). Efficient homogenization-ultrasound-assisted extraction of anthocyanins and flavonols from bog bilberry (Vaccinium uliginosum L.) marc with carnosic acid as an antioxidant additive. Molecules, 24 (14), 2537.

27. Yusong Jin, Zaizhi Liu, Dongmei Liu, Guangyu Shi, Dewen Liu, Yongfan Yang, Huiyan Gu,Lei Yang*, Zhiqiang Zhou. (2019). Natural antioxidant of rosemary extract used as an additive in the ultrasound-assisted extraction of anthocyanins from lingonberry (Vaccinium vitis-idaea L.) pomace. Industrial Crops and Products, 138, 111425.

28. Fengli Chen, Qiang Zhang, Huiyan Gu*, Lei Yang*. (2018). A modified approach for separating essential oil from the roots and rhizomes of Asarum heterotropoides var. mandshuricum. Journal of Cleaner Production, 172, 20752089.

29. Fengli Chen, Ming Xu, Xinyu Yang, Junling Liu, Yao Xiao, Lei Yang*. (2018). An improved approach for the isolation of essential oil from the leaves of Cinnamomum longepaniculatum using microwave-assisted hydrodistillation concatenated double-column liquid-liquid extraction. Separation and Purification Technology, 195, 110–120.

30. Fengli Chen, Jia Jia, Qiang Zhang, Lei Yang, Huiyan Gu. (2018). Isolation of essential oil from the leaves of Polygonum viscosum Buch-ham. using microwave-assisted enzyme pretreatment followed by microwave hydrodistillation concatenated with liquid–liquid extraction. Industrial Crops and Products, 112, 327341.

31. Zaizhi Liu, Lei Yang*. (2018). Antisolvent precipitation for the preparation of high polymeric procyanidin nanoparticles under ultrasonication and evaluation of their antioxidant activity in vitro. Ultrasonics Sonochemistry, 43, 208–218.

32. Guoqiang Cui, Xuebing Yang, Tingting Liu, Zaizhi Liu, Lei Yang*. (2018). An efficient approach for the enzyme-enhanced extraction of camptothecin and 10-hydroxycamptothecin from the samara of Camptotheca acuminate using an ionic liquid solution. Separation and Purification Technology, 200, 102–111.

33. Kexin Hou, Xuebing Yang, Meili Bao, Fengli Chen, Hao Tian, Lei Yang*. (2018). Composition, characteristics and antioxidant activities of fruit oils from Idesia polycarpa using homogenate-circulating ultrasound-assisted aqueous enzymatic extraction. Industrial Crops and Products, 117, 205215.

34. Xinyu Yang, Mengxia Wei, Hao Tian, Tingting Liu, Lei Yang. (2018). Enrichment and purification of aucubin from Eucommia ulmoides ionic liquid extract using macroporous resins. Materials, 11, 1758.

35. Zaizhi Liu, Huiyan Gu, Lei Yang. (2018). A novel approach for the simultaneous extraction of dihydroquercetin and arabinogalactan from Larix gmelinii by homogenate-ultrasound-synergistic technique using the ionic liquid. Journal of Molecular Liquids, 261, 41–49.

36. Guoqiang Cui, Zaizhi Liu, Mengxia Wei, Lei Yang. (2018).Turpentine as an alternative solvent for the extraction of gutta-percha from Eucommia ulmoides barks. Industrial Crops and Products, 121, 142–150.



关闭 打印责任编辑:陈华峰